Mucociliary transport using 99mTc-albumin colloid: a reliable screening test for primary ciliary dyskinesia

Mucociliary transport using 99mTc-albumin colloid: a reliable screening test for primary ciliary dyskinesia.

BACKGROUND A study was undertaken to assess the reliability of the nasal mucociliary transport test using 99mTc-albumin colloid as a screening test for primary ciliary dyskinesia (PCD) and to compare it with the gold standard nasal biopsy for study of ciliary motility and ultrastructure. METHODS During a 4 year period both tests were performed in 55 children referred with persistent or recurr...

AIRWAY BIOLOGY Mucociliary transport using Tc-albumin colloid: a reliable screening test for primary ciliary dyskinesia

Background: A study was undertaken to assess the reliability of the nasal mucociliary transport test using Tc-albumin colloid as a screening test for primary ciliary dyskinesia (PCD) and to compare it with the gold standard nasal biopsy for study of ciliary motility and ultrastructure. Methods : During a 4 year period both tests were performed in 55 children referred with persistent or recurren...

Pulmonary radioaerosol mucociliary clearance in primary ciliary dyskinesia.

Primary ciliary dyskinesia (PCD) is a genetic condition affecting one in 10 000–40 000 people from birth [1]; cilia fail to beat, and the airway clearance of mucus and debris is severely impaired. If untreated, this results in progressive lung infection leading to bronchiectasis and ultimately respiratory failure. Additionally, delayed diagnosis has implications for genetic counselling, appropr...

Primary ciliary dyskinesia.

Primary ciliary dyskinesia (PCD) is a rare genetic condition that affects the ciliary function of the respiratory tract, sperm tail, cilia of the embryonic node, and fallopian tube. The condition is characterized by impaired ciliary action, leading to recurrent lower-respiratory-tract infections, bronchiectasis, rhino-sinusitis, otitis media, impaired fertility in women, and infertility in men....

[Primary ciliary dyskinesia].